Publications

2020

Single cell genomic characterization reveals the cellular reprogramming of the gastric tumor microenvironment. Sathe A, Grimes SM, Lau BT, Chen J, Suarez C, Huang RJ, et al. Clin Cancer Res 2020.

2019

A functional CRISPR/Cas9 screen identifies kinases that modulate FGFR inhibitor response in gastric cancer. Chen, Jiamin & Bell, John & Lau, Billy & Whittaker, Tyler & Stapleton, Darren & Ji, Hanlee. (2019). A functional CRISPR/Cas9 screen identifies kinases that modulate FGFR inhibitor response in gastric cancer. Oncogenesis. 8. 10.1038/s41389-019-0145-z.

Single-cell transcriptome analysis identifies distinct cell types and niche signaling in a primary gastric organoid model. Chen, Jiamin & Lau, Billy & Andor, Noemi & Grimes, Susan & Handy, Christine & Wood-Bouwens, Christina & Ji, Hanlee. (2019). Single-cell transcriptome analysis identifies distinct cell types and niche signaling in a primary gastric organoid model. Scientific Reports. 9. 10.1038/s41598-019-40809-x.

Joint single cell DNA-Seq and RNA-Seq of gastric cancer reveals subclonal signatures of genomic instability and gene expression. Andor N, Lau B, Catalanotti C, Kumar J, Sathe A, Belhocine K, Wheeler T, Price A, Song M, Stafford D, Bent Z, DeMare L, Hepler L, Jett S, Lin B, Maheshwari S, Makareswicz A, Rahimi M, Sawhney S, Sauzade M, Shuga J, Sullivan-Bibee K, Weinstein A, Yang W, Yin Y, Kubit M, Chen J, Grime S, Suarez C, Poultsides G, Schnall-Levin M, Bharadwaj R, Ji H. 

2017

Linked read sequencing resolves complex genomic rearrangements in gastric cancer metastases. Greer, Stephanie & Nadauld, Lincoln & Lau, Billy & Chen, Jiamin & Wood-Bouwens, Christina & Ford, James & Kuo, Calvin & Ji, Hanlee. (2017). Linked read sequencing resolves complex genomic rearrangements in gastric cancer metastases. Genome Medicine. 9. 10.1186/s13073-017-0447-8.

2014

Metastatic tumor evolution and organoid modeling implicate TGFBR2 as a cancer driver in diffuse gastric cancer. Nadauld, Lincoln & Garcia, Sarah & Natsoulis, Georges & Bell, John & Miotke, Laura & Hopmans, Erik & Xu, Hua & Pai, Reetesh & Palm, Curt & Regan, John & Chen, Hao & Flaherty, Patrick & Ootani, Akifumi & Zhang, Nancy & Ford, James & Kuo, Calvin & Ji, Hanlee. (2014). Metastatic Tumor Evolution and Organoid Modeling Implicate TGFBR2 as a Cancer Driver in Diffuse Gastric Cancer. Genome biology. 15. 428. 10.1186/s13059-014-0428-9.